NewsBlaze search box Daily News header

Rheumatoid Arthritis Linked to Gut Bacteria

By  

Many "Auto immune" diseases such as Crohns, have eventually been found to be caused by a bacterial infection, now a devastating form of arthritis joins the list.

Science NOW, a daily publication of the AAAS, reported on November 4, 2013 that research to be published tomorrow in eLife shows a high correlation between Rheumatoid arthritis and an intestinal bacteria Provatella copri. Out of a sample of 114 individuals, 75% of those with that form or arthritis or recently diagnosed with it carried large quantities of P. copri, only 25% of healthy individuals had the bacteria.

Experiments with lab mice have produced similar results confirming a strong indication that the presence of an excessive amount of P. copri triggers an immune response specifically producing Th17 immune cells leading to the inflamed joints and damage caused by Rheumatoid arthritis.

A strong correlation with Psoriatic arthritis was also indicated in some tests.

The research was conducted by immunologist Diane Mathis of Harvard Medical School in Boston and Immunologist Dan Littman of New York University.

"That they were able to associate one bacterium with one pathology is remarkable," says Yasmine Belkaid, an immunologist at the National Institute of Allergy and Infectious Diseases in Bethesda, Maryland, who was not involved in the work.

The possibilities opened up by this discovery are extremely important because in the future, both forms of arthritis may be treated by using antibiotics instead of Remicade, the standard treatment for advanced Rheumatiod arthritis but the medication poses many risks including cancer and serious infections.

A MAP infection often triggers Crohns Disease and other gut bacteria also influence obesity and various allergies.

John McCormick is a reporter, /science/medical columnist and finance and social commentator, with 17,000+ bylined stories. He is a member of the AAAS and Science Editor of Perihelionsf.com. Contact John through NewsBlaze. Read more stories by John McCormick.

  Please leave a comment here     If it does not display within 10 seconds, please refresh the page

Related Health News News

Living with hemorrhoids? The good news is there are treatments available, both home remedies and medical treatments, that can significantly decrease the pain and discomfort.
June is National Acne Awareness Month. Acne is a growing problem, skyrocketing by over 200 percent in the past year. Here are some natural ways to treat it.
Salma Hayek, the 48-year-old superstar, says she does not exercise. Instead, she holds her body in such a way that keeps muscles activated all day long.
Health workers are warning of the dangers involved with the fashionable new trend of vaginal plumping - it won't be worth it if it doesn't work in the long term
As more and more people use cosmetic surgery to improve their bodies and faces, the General Medical Council (GMC) is urging plastic surgeons to give their patients more time to think.
The Journal of Clinical Oncology claims scientists used a genetically modified herpes virus to treat patients suffering from an aggressive form of skin melanoma.

 

NewsBlaze Writers Of The Month


Popular Stories This Month

newsletter logo

NewsBlaze
Copyright © 2004-2014 NewsBlaze Pty. Ltd.
Use of this website is subject to our Terms of Service and Privacy Policy  | DMCA Notice               Press Room   |    Visit NewsBlaze Mobile Site