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Codexis Reports Fourth Quarter and Full Year 2010 Results

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REDWOOD CITY, Calif., Feb. 3, 2011 /PRNewswire/ -- Codexis, Inc. (Nasdaq: CDXS) today announced financial results for the fourth quarter and year ended December 31, 2010.

Full Year 2010 Financial Highlights:

Revenue: Revenue increased 29% to $107.1 million, driven by a 77% increase in sales of pharmaceutical products, from $18.6 million in 2009 to $32.8 million in 2010, and increases in collaborative R&D and government grants.

Operating Expenses: Full year operating expenses increased 2% to $86.2 million. R&D expenses decreased 4% to $52.4 million, primarily from the elimination of royalty payments to Maxygen, Inc. as a result of our acquisition of Maxygen's gene shuffling IP portfolio in October, 2010. SG&A expenses increased 13% to $33.8 million driven by increases in compensation and benefits and outside services costs associated with becoming a public company.

Net Loss: Net loss was ($8.5) million, or ($0.35) per share, based on 24.6 million weighted average common shares outstanding for the full year 2010. This compares to a net loss of ($20.3) million in 2009.

Adjusted EBITDA: On a non-GAAP basis, Adjusted EBITDA was $9.9 million compared to a loss of ($7.3) million in 2009. Adjusted EBITDA is calculated by adjusting net loss for net interest expense, income taxes, depreciation, amortization, stock-based compensation and preferred stock warrant fair market valuation. A reconciliation of net loss to Adjusted EBITDA is presented below.

Fourth Quarter Financial Highlights:

Revenue: For the fourth quarter of 2010, the company reported revenues of $29.8 million, an increase of 23% from $24.2 million in the fourth quarter of 2009, primarily due to an increase of $3.4 million in product revenue, representing an increase of 67% over the same time period of 2009.

Operating Expenses: Research and development expenses in the fourth quarter of 2010 were $13.3 million, compared to $15.2 million for the fourth quarter of 2009. The decrease was primarily due to the reduction of royalty cost related to our acquisition of Maxygen's gene shuffling IP portfolio and a reduction of costs related to our joint development agreement with CO2 Solution. Selling, general and administrative expenses in the fourth quarter of 2010 declined to $8.6 million compared to $8.9 million over the same time period of 2009 primarily due to a reduction in discretionary expenses.

Net Loss: Net loss was ($0.5) million, or ($0.01) per share, based on 34.5 million weighted average common shares outstanding in the fourth quarter of 2010. This compares to a net loss of ($5.2) million or ($1.95) per share during the fourth quarter of 2009.

Adjusted EBITDA: On a non-GAAP basis, Adjusted EBITDA increased from ($1.1) million in the fourth quarter of 2009 to $4.4 million in the fourth quarter of 2010. Adjusted EBITDA is calculated by adjusting net loss for net interest expense, income taxes, depreciation, amortization, stock-based compensation and preferred stock warrant fair market valuation. A reconciliation of net loss to Adjusted EBITDA is presented below.

Cash: Cash, and cash equivalents at December 31, 2010, decreased to $72.4 million compared to $99.3 million at September 30, 2010 primarily due to our $20.0 million purchase of the Maxygen, Inc. gene shuffling IP portfolio in October 2010 and our $3.7 million debt repayment.

"In addition to our solid financial results, we continued to exceed our goals in our targeted commercial opportunities," said Alan Shaw, president and CEO of Codexis. "We achieved our technical milestones with Shell, we made our first shipments of two important enzymes to Merck and we saw substantial progress in our efforts in carbon capture and chemicals."

Outlook

Codexis' statements with regard to its outlook are based on current expectations. The following statements are forward looking, and actual results could differ materially depending on market conditions and the factors set forth under "Forward-Looking Statements" below.

For the full year 2011, Codexis forecasts revenues of $120 million or greater, which would represent growth of 12% or greater compared to 2010. Codexis expects 2011 Adjusted EBITDA will be $5 million or greater.

Conference Call

Codexis will hold a conference call for investors on February 3, 2011 at 1:30 p.m. PT (4:30 p.m. ET). The conference call dial-in numbers are US: 866-788-0541 or International: 857-350-1679, access code 54501345. A live webcast of the call will also be available from the Investor Relations section of www.codexis.com. A recording of the call will be available by calling US: 888-286-8010 or International: 617-801-6888, access code 91197822 beginning approximately two hours after the call, and will be available for up to thirty days. A webcast replay from today's call will also be available from the Investor Relations section of www.codexis.com approximately two hours after the call and will be available for up to thirty days.

About Codexis, Inc.

Codexis is a clean technology company. Codexis develops optimized biocatalysts that make industrial processes faster, cleaner and more efficient. Codexis' technology is commercialized with leading global pharmaceutical companies and in development for advanced biofuels with Shell and carbon capture with Alstom. Other potential markets for the company's biocatalyst-enabled solutions include chemicals and water treatment.

Forward-Looking Statements

This press release contains forward-looking statements relating to the company's forecast for 2011 revenue and Adjusted EBITDA, which is defined elsewhere in this press release. You should not place undue reliance on these forward-looking statements because they involve known and unknown risks, uncertainties and other factors that are, in some cases, beyond our control and that could materially affect actual results. Factors that could materially affect actual results can be found in Codexis' Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on November 4, 2010, included under the caption "Risk Factors." Codexis expressly disclaims any intent or obligation to update these forward-looking statements, except as required by law.


                      Codexis, Inc.
     Condensed Consolidated Statements of Operations
                       (Unaudited)
        (In Thousands, Except Per Share Amounts)

                                         Three Months Ended
                                            December 31,
                                            ------------
                                         2010          2009  % change
                                         ----          ----  --------
      Revenues:
           Product                     $8,586        $5,152         67%
           Related party collaborative
            research and development   19,275        18,693          3%
           Collaborative research and
            development                 1,471           358        311%
           Government grants              479            35         nm
                                          ---           ---

          Total revenues               29,811        24,238         23%
                                       ------        ------

      Costs and operating expenses:
           Cost of product revenues     8,126         4,792         70%
                Gross margin $            460           360
    Gross margin %                         5%            7%
           Research and development    13,349        15,240        -12%
           Selling, general and
            administrative              8,649         8,932         -3%
                                        -----         -----

      Total costs and operating
       expenses                        30,124        28,964          4%
                                       ------        ------

      Loss from operations               (313)       (4,726)       -93%

           Interest income                 31            39        -21%
           Interest expense and other,
            net                          (153)         (507)       -70%
      Loss before provision
       (benefit) for income taxes        (435)       (5,194)       -92%
           Provision (benefit) for
            income taxes                   60           (13)        nm
                                          ---           ---
      Net loss                          $(495)      $(5,181)       -90%
                                        =====       =======

      Net loss per share of common
       stock,
      basic and diluted                $(0.01)       $(1.95)
                                       ======        ======

      Weighted average common
       shares used in computing net
       loss per share of common
       stock, basic and diluted        34,452         2,653
                                       ======         =====


                                           Twelve Months Ended
                                               December 31,
                                               ------------
                                            2010           2009  % change
                                            ----           ----  --------
      Revenues:
           Product                       $32,835        $18,554         77%
           Related party collaborative
            research and development      66,148         62,656          6%
           Collaborative research and
            development                    4,048          1,652        145%
           Government grants               4,073             46         nm
                                           -----            ---

          Total revenues                 107,104         82,908         29%
                                         -------         ------

      Costs and operating
       expenses:
           Cost of product revenues       27,982         16,678         68%
                Gross margin $             4,853          1,876
    Gross margin %                           15%            10%
           Research and development       52,405         54,725         -4%
           Selling, general and
            administrative                33,841         29,871         13%
                                          ------         ------

      Total costs and operating
       expenses                          114,228        101,274         13%
                                         -------        -------

      Loss from operations                (7,124)       (18,366)       -61%

           Interest income                   166            180         -8%
           Interest expense and other,
            net                           (1,199)        (2,037)       -41%
      Loss before provision
       (benefit) for income taxes         (8,157)       (20,223)       -60%
           Provision (benefit) for
            income taxes                     384             66        482%
                                             ---            ---
      Net loss                           $(8,541)      $(20,289)       -58%
                                         =======       ========

      Net loss per share of
       common stock,
      basic and diluted                   $(0.35)        $(7.74)
                                          ======         ======

      Weighted average common
       shares used in computing
       net loss per share of
       common stock, basic and
       diluted                         24,594       2,622
                                          ======          =====

      Codexis, Inc.
      Condensed Consolidated Balance Sheets
      (Unaudited)
      (In Thousands)

                                                    December   December
                                                       31,        31,
                                                         2010       2009
                                                         ----       ----
     Assets
     Current assets:
        Cash and cash equivalents                     $72,396    $31,785
        Marketable securities                               -     23,778
        Accounts receivable, net                       10,620      7,246
        Related party accounts receivable               4,713          -
        Inventories                                     2,817      2,915
        Prepaid expenses and other current assets       1,646      1,658
                                                        -----      -----
           Total current assets                        92,192     67,382

     Restricted cash                                    1,466        731
     Property and equipment, net                       21,452     21,581
     Intangible assets, net                            20,158        928
     Goodwill                                           3,241      3,241
     Other non-current assets                           2,791      5,173
                                                        -----      -----
         Total assets                                $141,300    $99,036
                                                     ========    =======

     Liabilities, redeemable convertible
      preferred stock, and shareholders' equity
      (deficit)
     Current liabilities:
        Accounts payable                               $9,208     $9,999
        Accrued compensation                            8,107      6,518
        Related party payable                               -      1,314
        Other accrued liabilities                       5,630     10,376
        Redeemable convertible preferred stock
         warrant liability                                  -      2,009
        Deferred revenues                                 455      2,240
        Related party deferred revenues                 4,084     13,161
        Financing obligations                               -      5,368
           Total current liabilities                   27,484     50,985

     Deferred revenues, net of current portion          1,671      1,856
     Related party deferred revenues, net of
      current portion                                   3,403      7,487
     Financing obligations, net of current
      portion                                               -      2,574
     Other long-term liabilities                        1,381      1,307
                                                        -----      -----
           Total  liabilities                          33,939     64,209

     Redeemable convertible preferred stock
      issuable in series A to F                             -    179,672

     Stockholders' equity (deficit):
     Common stock                                           4          -
     Additional paid-in capital                       275,540     15,015
     Accumulated other comprehensive loss                 (34)      (252)
     Accumulated deficit                             (168,149)  (159,608)
                                                     --------   --------
           Total  stockholders' equity (deficit)      107,361   (144,845)
                                                      -------   --------
         Total liabilities, redeemable convertible
          preferred stock, and shareholders' equity
          (deficit)                                  $141,300    $99,036
                                                     ========    =======

      Codexis, Inc.
      Condensed Consolidated Statements of Cash Flow
      (Unaudited)
      (In Thousands)

                                                     Twelve Months
                                                         Ended
                                                     December 31,

                                                     2010           2009
                                                     ----           ----
     Operating activities:
       Net loss                                   $(8,541)      $(20,289)
       Adjustments to reconcile net loss to
        net cash used in operating
        activities:
             Amortization of intangible assets      1,063            957
             Depreciation and amortization of
              property and equipment                7,246          5,172
             Revaluation of redeemable
              convertible preferred stock warrant
              liability                               677            627
             Loss (gain) on disposal of property
              and equipment                           148            (50)
             Extinguishment of royalty payable        461              -
             Stock-based compensation               8,737          4,822
             Accretion of asset retirement
              obligation                              146             43
             Amortization of debt discount             26            311
             Accretion (amortization) of premium/
              discount on marketable securities       511            594
             Changes in operating assets and
              liabilities:
               Accounts receivable                 (8,087)        (1,054)
               Inventories                             98             58
               Prepaid expenses and other current
                assets                                 13             11
               Other assets                         2,814           (228)
               Accounts payable                      (791)           189
               Accrued compensation                 1,589          2,434
               Related party payable               (1,314)           879
               Other accrued liabilities           (6,048)        (3,792)
               Deferred revenues                  (15,131)           530
                                                  -------            ---
                  Net cash used in operating
                   activities                     (16,383)        (8,786)
                                                  -------         ------
     Investing activities:
           (Increase) decrease  in restricted
            cash                                     (735)           193
           Purchase of property and equipment      (6,990)       (10,697)
           Purchase of marketable securities      (49,051)       (37,118)
           Purchase of Maxygen patent portfolio   (20,705)             -
           Proceeds from sale of marketable
            securities                              1,605              -
           Proceeds from maturities of
            marketable securities                  70,695         27,980
           Proceeds from disposal of property
            and equipment                              15              -
           Purchase of CO2 Solution common
            shares                                      -         (1,316)
               Net cash provided by (used in)
                investing activities               (5,166)       (20,958)
                                                   ------        -------
     Financing activities:
           Principal payments on financing
            obligations                            (8,026)        (6,087)
           Payments in preparation for initial
            public offering                        (3,870)          (959)
           Proceeds from issuance of preferred
            stock, net of issuance costs                -         46,926
           Proceeds from issuance of common
            stock on IPO, net of underwriting
            discounts                              72,541              -
           Proceeds from exercises of stock
            options                                 1,594            117
                                                    -----            ---
               Net cash provided by financing
                activities                         62,239         39,997
                                                   ------         ------

         Effect of exchange rate changes on
          cash and cash equivalents                   (79)          (371)
                                                      ---           ----

     Net increase in cash and cash
      equivalents                                  40,611          9,882
     Cash and cash equivalents:
        Beginning of the period                    31,785         21,903
                                                   ------         ------
        End of the period                          72,396         31,785

        Marketable securities at the end of
         period                                         -         23,778

     Cash, cash equivalents and
      marketable securities                       $72,396        $55,563
                                                  =======        =======

Reconciliation of GAAP to Non-GAAP Financial Information

In this press release, in addition to GAAP financial results, we present Adjusted EBITDA because we believe it assists investors and analysts in comparing our performance across reporting periods on a consistent basis by excluding items that we do not believe are indicative of our core operating performance. In addition, we use Adjusted EBITDA as a factor in evaluating management's performance when determining incentive compensation and to evaluate the effectiveness of our business strategies.

A reconciliation of GAAP net loss to Adjusted EBITDA is included in the table below.


                               Codexis, Inc.
            Reconciliation of GAAP Net Loss to Adjusted EBITDA
                                (Unaudited)
                              (In Thousands)

                                      Three months      Twelve months
                                          ended             ended
                                      December 31,      December 31,
    Calculation of Adjusted EBITDA   2010          2009     2010        2009
    ------------------------------   ----          ----     ----        ----
    Net loss                        $(495)      $(5,181) $(8,541)   $(20,289)
    Adjustments:
    Minus: Interest income            (31)          (39)    (166)       (180)
    Plus: Interest expense              5           336      529       1,413
    Plus: Income taxes                 60           (13)     384          66
    Plus: Depreciation and
     amortization                   2,593         1,713    8,266       6,119
    Plus: Stock-based compensation  2,296         1,763    8,728       4,912
    Plus: Preferred stock warrant
     fair market valuation
     adjustment                         -           277      677         627

       Adjusted EBITDA             $4,428       $(1,144)  $9,877     $(7,332)
                                   ======       =======   ======     =======

Adjusted EBITDA has limitations as an analytical tool. Some of these limitations are:

    --  Adjusted EBITDA does not reflect our cash expenditures, or future
        requirements, for capital expenditures or contractual commitments;
    --  Adjusted EBITDA does not reflect changes in, or cash requirements for,
        our working capital needs;
    --  Although depreciation and amortization are non-cash charges, the assets
        being depreciated and amortized will often have to be replaced in the
        future, and Adjusted EBITDA does not reflect any cash requirements for
        such replacements; and
    --  Non-cash compensation is and will remain a key element of our overall
        long-term incentive compensation package, although we exclude it as an
        expense when evaluating our ongoing operating performance for a
        particular period.

Because of these limitations, Adjusted EBITDA should not be considered in isolation or as a substitute for performance measures calculated in accordance with GAAP. We compensate for these limitations by relying primarily on our GAAP results and using Adjusted EBITDA only supplementally.



    Contacts:
    Investors:   Robert Lawson, robert.lawson@codexis.com, 650-421-8137
    Media: Lyn Christenson, lyn.christenson@codexis.com, 650-421-8144 or
     Saskia Sidenfaden, ssidenfaden@mww.com, 212-827-3771.

SOURCE Codexis, Inc.



 
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