Published: June 04, 2010
R-Tech Ueno Discloses Results of Phase 2 Retinitis Pigmentosa Clinical Trial
BETHESDA, Md. - (BUSINESS WIRE) - Sucampo Pharmaceuticals, Inc. (NASDAQ: SCMP) today confirmed that its
partner, R-Tech Ueno, Ltd. ("RTU" ) (Osaka Securities Exchange Hercules
code: 4573), reported the results of its recently completed phase 2
clinical trial of UF-021 in retinitis pigmentosa patients. The results
showed improvement in visual function dose-dependently in both visual
field test and subjective findings. Furthermore, although there was an
irritation upon instillation, there were no severe adverse effects.
This was a multi-center, randomized, double blind, three parallel group,
placebo controlled study conducted according to current Good Clinical
Practice (cGCP). This phase 2 clinical study of UF-021 was conducted in
112 mid-stage to late-stage retinitis pigmentosa patients.
In April 2009, Sucampo licensed from RTU the development and
commercialization rights to UF-021 for the United States and Canada,
including all associated patents, improvements and other intellectual
property owned, controlled and developed by RTU.
The data from this trial is undergoing further analysis and will be
submitted to an appropriate scientific conference for presentation.
Retinitis pigmentosa is a genetic disease characterized by progressive,
irreversible vision loss and decreasing visual acuity. As RP progresses,
daily life becomes increasingly more difficult. Blindness from all
causes is among the most significant injuries to a patient's quality of
life and is a major driver of patient-based cost of care and life-style
maintenance. There are no drugs or therapeutic procedures currently
approved for the treatment of RP today.
About R-Tech Ueno, Ltd.
R-Tech Ueno is a bio venture company established in September 1989 for
the purpose of marketing and R&D of drugs. Under leadership of the CEO,
also a medical doctor, the company is developing new drugs on the theme
of "Physician-Oriented New Drug Innovation" , targeting ophthalmologic
and dermatologic diseases that previously had no effective therapeutic
agent. We aim at becoming a "global pharmaceutical company specializing
in specific fields (ophthalmology and dermatology) and selling and
developing pharmaceutical products through the eyes of doctors." We are
promoting development of new drugs for unmet medical needs (medical
needs that are not fulfilled yet) which the Japanese government
recommends and assists, orphan drugs and the drugs in the field of
anti-aging (lifestyle drugs).
About Sucampo Pharmaceuticals, Inc.
Sucampo Pharmaceuticals, Inc., an international biopharmaceutical
company based in Bethesda, Maryland, focuses on the development and
commercialization of medicines based on prostones. The therapeutic
potential of prostones, which are bio-lipids that occur naturally in the
human body, was first identified by Ryuji Ueno, M.D., Ph.D., Ph.D.,
Sucampo Pharmaceuticals' Chairman and Chief Executive Officer.
Sucampo markets Amitiza(R) (lubiprostone) 24 mcg in the U.S.
for chronic idiopathic constipation in adults and Amitiza 8 mcg in the
U.S. to treat irritable bowel syndrome with constipation in adult women.
Sucampo also is developing the drug for additional gastrointestinal
disorders with large potential markets. In addition, Sucampo has a
robust pipeline of compounds with the potential to target underserved
diseases affecting millions of patients worldwide.
Sucampo Pharmaceuticals, Inc. has four wholly owned subsidiaries:
Sucampo Pharma Europe, Ltd., located in the UK; Sucampo Pharma, Ltd.,
located in Japan; Sucampo Manufacturing & Research AG, located in
Switzerland; and, Sucampo Pharma Americas, Inc., located in Maryland. To
learn more about Sucampo Pharmaceuticals Inc. and its products, visit www.sucampo.com.
Sucampo Forward Looking Statement
Any statements in this press release about future expectations, plans
and prospects for Sucampo Pharmaceuticals are forward-looking statements
made under the provisions of The Private Securities Litigation Reform
Act of 1995. Forward-looking statements may be identified by the words
"project," "believe," "anticipate," "plan," "expect," "estimate,"
"intend," "should," "would," "could," "will," " may" or other similar
expressions. Forward-looking statements include statements about
potential growth in the prevalence of particular diseases or conditions,
including retinitis pigmentosa, the potential utility of UF-021 to treat
retinitis pigmentosa and additional indications and future clinical
trials. Actual results may differ materially from those indicated by
such forward-looking statements as a result of various important
factors, including those described in Sucampo Pharmaceuticals' filings
with the Securities and Exchange Commission (SEC), including the annual
report on Form 10-K for the year ended December 31, 2009 and other
periodic reports filed with the SEC. Any forward-looking statements in
this press release represent Sucampo Pharmaceuticals' views only as of
the date of this release and should not be relied upon as representing
its views as of any subsequent date. Sucampo does not undertake any
obligation to update any forward-looking statements contained in this
release as a result of new information, future events or otherwise,
except as required by law.

Sucampo Pharmaceuticals, Inc.
Kate de Santis
1-240-223-3834
kdesantis@sucampo.com
or
Westwicke
Partners, LLC
John Woolford
1-443-213-0506
john.woolford@westwickepartners.com
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