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TIBCO Spotfire Executive, Customer to Speak at Leading Life Sciences Events in April

TIBCO Software Inc. (NASDAQ: TIBX) today announced that TIBCO Spotfire's Senior Director of Life Sciences Clinical Practice, Dr. Michael O'Connell, will present at a leading life sciences event this month, the Drug Development Congress 2010 being held on April 22-23, 2010 in London, U.K. In addition, TIBCO Spotfire customer Infinity Pharmaceuticals will also present at the Bio-IT World Conference & Expo '10 being held April 20-22, 2010 in Boston, Mass. Since its debut in 2002, the Bio-IT World Conference & Expo has established itself as a premier event showcasing the myriad applications of IT and informatics to biomedical research and the drug discovery enterprise.

Participation details regarding each conference are as follows:

What:        TIBCO Spotfire Senior Director of Life Sciences, Dr. Michael
             O'Connell, will present a session entitled 'Safety Data
             Visibility and Analytics for Risk Management in Drug
             Development' at the Drug Development Congress 2010.

             Session Overview: The session will explore drug safety and risk
             assessment as well as reducing bottlenecks in drug development,
             including new technologies and references to case studies from
             multiple therapy areas.

             Session attendees will learn about:
             -- Safety data analysis technologies throughout drug
                development
             -- CIOMS VI, SPERT and FDA guidelines
             -- Visualization and statistical analytics for safety
                assessment
             -- Signal detection and management of false positives
             -- Interactive exploratory review and patient profiling
             -- Collaboration across clinical program teams through data
                visualization

Where:       The conference is being held on April 22-23, 2010 at the
             Copthorne Tara Hotel London Kensington in London, U.K.
When:        Dr. O'Connell will present on Thursday, April 22, 2010 at
             11:40 a.m. local time.
Information: For more information about the Drug Development Congress,
             visit: http://www.drugdevelopment-summit.com/index.asp.

-------------------

What:        Infinity Pharmaceuticals Inc., a TIBCO Spotfire customer, will
             present at the Bio-IT World Conference & Expo '10. John Walker,
             associate director of clinical informatics at Infinity
             Pharmaceuticals, will lead a session entitled 'Making Clinical
             Data Integration Work in a Heterogeneous Environment.'

             Session Overview: Infinity Pharmaceuticals' clinical
             infrastructure has evolved over the past five years to
             accommodate trials of varying phase, indication and breadth.
             Execution of the trials involves a hybrid of internal and
             external resources leading the team to create an architecture
             that supports information sharing across organizations. The
             integrated architecture, comprised of the following systems:
             CTMS, Pharmacovigilance, EDC and a CDISC-compliant data
             warehouse, contains validated and commercial off-the-shelf
             components interspersed with not validated and custom software.
             Automated reporting and a progressive approach to data
             visualization and analysis have led to broad use of the
             platform throughout the company. This adoption has improved
             communication between groups and facilitated more efficient
             strategic and tactical decision-making.

Where:       The conference is being held on April 20-22, 2010 at the World
             Trade Center in Boston, Mass.
When:        Mr. Walker will present on Thursday, April 22, 2010 at
             11:00 a.m. local time.
Information: For more information about the Bio-IT World Conference & Expo,
             visit: http://www.bio-itworldexpo.com/.

Currently, nine of the top ten global pharmaceutical and biotech companies leverage the TIBCO Spotfire® platform to drive shorter development cycles and faster approvals of drugs that are safe and effective. To learn more about TIBCO Spotfire's next generation of life science research products, visit: http://spotfire.tibco.com/spotfire-for-you/by-industry/life-sciences/life-sciences-analytics.aspx.

About TIBCO
TIBCO Software Inc. (NASDAQ: TIBX) is a leading provider of enterprise analytics software for next generation business intelligence. TIBCO Spotfire products offer a visual and interactive experience that helps professionals quickly discover new and actionable insights in information. Distinguished by its speed to insight and adaptability to specific business challenges, Spotfire rapidly reveals unseen threats and new opportunities, creating significant economic value. Spotfire customers include industry leaders among the Global 2000 that have deployed Spotfire analytics to gain an information advantage over their competitors. For more information, visit http://spotfire.tibco.com.

TIBCO, TIBCO Software, TIBCO Spotfire, and Spotfire are trademarks or registered trademarks of TIBCO Software Inc. or its subsidiaries in the United States and/or other countries. All other product and company names and marks mentioned in this document are the property of their respective owners and are mentioned for identification purposes only.