Published: March 11, 2010
Advaxis Develops Room Temperature Formulation of ADXS11-001
NORTH BRUNSWICK, N.J. - (BUSINESS WIRE) - Advaxis,
Inc., (OTCBB: ADXS), the live, attenuated Listeria
monocytogenes (Listeria) immunotherapy company has developing
a long-term, room temperature, storage-stable form of its vaccines. This
would replace the current requirement to keep the product frozen at -70o
C before use.
Advaxis has been investigating other methods for preserving its live
vaccines without the need for freezing. Although live Listeria
can be freeze dried, this method is associated with a loss of 90% or
more of the bacterial activity. A recent test of a different method,
called "foam drying" has delivered a product, which is stable at room
temperature. Recovery of almost 100% of the product was observed and
excellent biological activity was seen.
"This exciting work can make it possible to distribute our products to
every physician's office without special equipment using a low cost
process," commented Advaxis Chairman/CEO Thomas A. Moore. "It will be
key to the licensing and commercialization of all our vaccine
technologies."
About Advaxis, Inc.
Advaxis is a biotechnology company developing proprietary, live,
attenuated Listeria monocytogenes (Listeria)
immunotherapeutics that deliver engineered tumor antigens, which
stimulate multiple, simultaneous, immunological mechanisms to fight
cancer. Today, the Company has nine (9) distinct, cancer-fighting
constructs in various stages of development, directly and through
strategic collaborations with such recognized sites of excellence as the City
of Hope, the Roswell
Park Cancer Institute, the National
Cancer Institute, the University
of Pittsburgh and Cancer
Research - UK. The Company's technology was developed by Dr. Yvonne
Paterson, professor of microbiology at the University of Pennsylvania
and chairperson of Advaxis' scientific advisory board. Please visit the
Company's portals: advaxis.com
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Forward-Looking Statements
Certain statements contained in this press release are
forward-looking statements that involve risks and uncertainties. The
statements contained herein that are not purely historical are forward
looking statements within the meaning of Section 27A of the Securities
Act of 1933, as amended, and Section 21E of the Securities Exchange Act
of 1934, as amended. Forward-looking statements deal with the
Company's current plans, intentions, beliefs and expectations and
statements of future economic performance. Forward-looking
statements involve known and unknown risks and uncertainties that may
cause the Company's actual results in future periods to differ
materially from what is currently anticipated. Factors that could
cause or contribute to such differences include those discussed from
time to time in reports filed by the Company with the Securities and
Exchange Commission. The Company cannot guarantee its future
results, levels of activity, performance or achievements.

For Further Information:
Advaxis, Incorporated
Conrad
F. Mir, 732-545-1590
Executive Director
Fax: 732-545-1084
mir@advaxis.com
www.advaxis.com
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