Published:
Genmab Reaches Fifth Milestone in Ofatumumab Collaboration
COPENHAGEN, August 21 /PRNewswire-FirstCall/ -- Genmab A/S (OMX: GEN)
announced today it has reached the fifth milestone for ofatumumab
(HuMax-CD20(R)) under the terms of its collaboration with GlaxoSmithKline
(GSK). A milestone payment of approximately DKK 232.7 million (approximately
USD 48.5 million) was triggered by the achievement of positive results in the
Phase III study of ofatumumab in refractory chronic lymphocytic leukemia
(CLL). Genmab has received an approximate total of DKK 552 million
(approximately USD 110 million) in milestone payments under the collaboration
so far.
"While achievement of this milestone represents an important potential
turning point for Genmab," said Lisa N. Drakeman, Ph.D., Chief Executive
Officer of Genmab, "it is even more important for CLL patients who are
waiting for new treatments to combat their difficult to treat disease."
Ofatumumab is an investigational new generation fully human monoclonal
antibody that targets a distinct, membrane proximal, small loop epitope
(specific antibody binding site) of the CD20 molecule on B cells. Ofatumumab
is being developed to treat CLL, follicular non-Hodgkin's lymphoma, diffuse
large B-cell lymphoma, rheumatoid arthritis and relapsing remitting Multiple
Sclerosis under a co-development and commercialization agreement between
Genmab and GlaxoSmithKline. It is not yet approved in any country.
About Genmab A/S
Genmab is a leading international biotechnology company focused on
developing fully human antibody therapeutics for unmet medical needs. Using
cutting-edge antibody technology, Genmab's world class discovery, development
and manufacturing teams have created and developed an extensive pipeline of
products for potential treatment of a variety of diseases including cancer
and autoimmune disorders. As Genmab advances towards a commercial future, we
remain committed to our primary goal of improving the lives of patients who
are in urgent need of new treatment options. For more information on Genmab's
products and technology, visit http://www.genmab.com.
This press release contains forward looking statements. The words
"believe", "expect", "anticipate", "intend" and "plan" and similar
expressions identify forward looking statements. Actual results or
performance may differ materially from any future results or performance
expressed or implied by such statements. The important factors that could
cause our actual results or performance to differ materially include, among
others, risks associated with product discovery and development,
uncertainties related to the outcome and conduct of clinical trials including
unforeseen safety issues, uncertainties related to product manufacturing, the
lack of market acceptance of our products, our inability to manage growth,
the competitive environment in relation to our business area and markets, our
inability to attract and retain suitably qualified personnel, the
unenforceability or lack of protection of our patents and proprietary rights,
our relationships with affiliated entities, changes and developments in
technology which may render our products obsolete, and other factors. For a
further discussion of these risks, please refer to the section "Risk
Management" in Genmab's Annual Report, which is available on
http://www.genmab.com. Genmab does not undertake any obligation to update or
revise forward looking statements in this press release nor to confirm such
statements in relation to actual results, unless required by law.
Genmab(R); the Y-shaped Genmab logo(R); HuMax(R); HuMax-CD4(R);
HuMax-CD20(R); HuMax-EGFr(TM); HuMax-IL8(TM); HuMax-TAC(TM); HuMax-HepC(TM);
HuMax-CD38(TM); HuMax-CD32b(TM) and UniBody(R) are all trademarks of Genmab
A/S.
SOURCE Genmab A/S
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