Study Finds Nearly One-Third of All Inexpensive Earrings Examined Tested Positive for Nickel

In the report entitled, "Nickel release from earrings purchased inthe United States: TheSan Francisco earring study," published online in the Journal of the American Academy of Dermatology, dermatologist Howard I. Maibach, MD, FAAD, professor of dermatology at the University of California, San Francisco, presented evidence that nickel exposure from inexpensive earrings purchased from various stores and vendors is frequent inthe United States and does not correlate with the price of the earrings within the "inexpensive" price range.

"Sensitization to nickel is quite common inthe United States, with studies estimating that 5.8 percent of American adults tested positive to nickel allergy through a routine skin test," said Dr. Maibach. "In the early 1990s, the European Union Nickel Directive was passed in an effort to decrease the prevalence of nickel sensitization in consumer and occupational products inEurope, with results indicating the directive is working. However, no such regulations exist inthe United States to limit nickel exposure -- leaving millions of people at risk for dermatitis from common goods, such as earrings."

For the study, Dr. Maibach and his collaborator, Jacob Pontoppidan Thyssen, MD, purchased inexpensive earrings from 34 different stores and artists inSan Francisco in October 2007. Inexpensive earrings were classified as those under $50; in contrast, expensive earrings were classified as those made of gold or platinum available from fine jewelry stores. A total of 277 earrings were purchased from four different categories of vendors -- a downtown market with licensed local artists producing custom-made jewelry; jewelry stores in China Town targeting mainly tourists; national and international clothing and accessory chain stores targeting mainly girls and women under age 40; and similar stores targeting mainly women over age 40.

All earrings purchased were examined with the dimethylglyoxime (DMG) test -- a routine spot test using solutions to detect the presence of nickel and other alloys. Of the 277 earrings that were tested, 85 (or 30.7 percent) demonstrated at least one spot that tested DMG-positive for nickel. Dr. Maibach noted that the highest proportion of DMG-positive earrings was purchased from local artists, with 69 percent of these earrings testing positive for nickel. A large portion (42.9 percent) of earrings purchased from stores in China Town also tested positive for nickel.

When the number of DMG-positive earrings was examined from accessory and clothing stores targeting younger women under age 40 and those stores targeting women over age 40, Dr. Maibach found a large discrepancy. Specifically, 24.1 percent of the earrings purchased at the stores targeting younger women tested positive for nickel; whereas only 1.7 percent of earrings from stores targeting women over 40 tested DMG positive.

"Except for one store targeting girls and young women where a significant number of DMG-positive earrings were found, the proportion of earrings that tested positive for nickel was generally higher among individual China Town stores and local artists than in individual national and international chain stores," said Dr. Maibach. "We also found no correlation between the country where the earrings were manufactured and the frequency of DMG-positive reactions or whether the price of the inexpensive earrings correlated with testing positive for nickel exposure."

Dr. Maibach added that in one accessory store, none of the 44 earrings priced between $5 and $8 were DMG positive, whereas numerous earrings priced between $15 and $25 in another accessory store were DMG positive.

"From our findings, we could not establish a 'safe-limit price' as a guide for consumers who want to avoid excessive nickel exposure when purchasing inexpensive earrings," said Dr. Maibach. "But it's safe to say that young customers purchasing earrings at a considerable price range in U.S. chain stores are potentially at risk of nickel exposure and sensitization."

Studies show that nickel sensitization increases the risk of hand eczema, but Dr. Maibach argued that avoiding nickel -- which is found almost everywhere -- can be difficult. He acknowledged that there are some patients with nickel dermatitis who refuse to give up their jewelry, even when they know it is the cause of their condition. Since the best way to avoid nickel sensitization and subsequent dermatitis is to prevent nickel exposure, Dr. Maibach suggested the following tips:

    -- Look for jewelry and clothing labeled "nickel-free" or "hypoallergenic"
    -- Wear only stainless steel, platinum or gold jewelry if you know you are
       allergic to nickel
    -- Discontinue wearing jewelry that causes any noticeable skin irritation,
       such as redness or itching
    -- Use 1% hydrocortisone cream or ointment, which can be purchased
       over-the-counter, to treat nickel-induced dermatitis
    -- See your dermatologist if symptoms worsen or do not improve within
       three to five days of not wearing jewelry

Headquartered inSchaumburg, Ill., the American Academy of Dermatology (Academy), founded in 1938, is the largest, most influential, and most representative of all dermatologic associations. With a membership of more than 15,000 physicians worldwide, the Academy is committed to: advancing the diagnosis and medical, surgical and cosmetic treatment of the skin, hair and nails; advocating high standards in clinical practice, education, and research in dermatology; and supporting and enhancing patient care for a lifetime of healthier skin, hair and nails. For more information, contact the Academy at 1-888-462-DERM (3376) or http://www.aad.org.

SOURCE American Academy of Dermatology

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