Published:
Althea Technologies Chosen by Quintessence Biosciences to Produce Lead Protein Oncology Drug

Althea Technologies, Inc., a leading provider
of innovative technologies and services for pharmaceutical development and
manufacturing, announced today that it has been awarded a contract from
Quintessence Biosciences under a manufacturing supply agreement to produce
the firm's first drug candidate. The drug candidate QBI-139 is effective
in cancer models against a broad range of solid tumors. Quintessence plans
to file an investigational new drug application (IND) for QBI-139 with the
U.S. Food and Drug Administration (FDA) in the first quarter of 2008.
Althea will provide protein production, purification, and aseptic filling
services to produce the clinical trial materials.
"Althea is an outstanding company with significant experience in the
contract manufacture of protein therapeutics," said Ralph Kauten,
Quintessence Biosciences CEO. "We are confident in their ability to produce
the quality of drug we need for our upcoming clinical trials."
"We are very pleased to begin work on Quintessence's leading drug
candidate," stated President and Co-CEO of Althea, Dr. Magda Marquet. "The
Quintessence QBI-139 therapeutic program is exciting as it represents a new
and potentially safer approach to combat a broad array of devastating
cancer types."
About Althea Technologies, Inc.
Althea Technologies, a leading San Diego-based pharmaceutical services
firm, provides critical manufacturing and development services that support
researchers worldwide in their advancement of novel therapies and efforts
to apply new genomic information. Althea's services include cGMP contract
manufacturing of recombinant proteins, DNA-based therapeutics and vaccines,
aseptic filling, and gene quantification using real-time PCR and gene
expression analysis under GLP conditions. Additionally, Althea has
introduced new services and technologies for the identification and
development of genetic biomarkers with innovative programs such as the
company's proprietary Express Pathway(SM). For more information, visit
www.altheatech.com.
About the Evade Ribonucleases
The Evade Ribonuclease technology provides an opportunity to attack the
RNA in cancer cells, an exciting new cancer drug target, with analogs of
the human pancreatic ribonuclease 1. In preclinical disease models, the
most advanced lead candidate QBI-139 has shown an exceptional safety
profile and outstanding tumor growth inhibition in vivo against human
pancreatic, non-small cell lung, prostate, and ovarian solid tumors.
About Quintessence Biosciences, Inc.
Quintessence Biosciences, Inc. is a private biopharmaceutical company
focused on development of proprietary cancer therapies based on the Evade
Ribonuclease technology. Quintessence's first product candidate, QBI-139,
is anticipated to enter a Phase 1 clinical trial in the first half of 2008.
The company also has a pipeline of other Evade Ribonuclease products in
preclinical research. For more information, visit www.quintbio.com.
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