Published:
National Kidney Registry Announces Results of Recent Match Runs Where the First Perfect Matches Were Found Among Strangers

Today, at a presentation to the leadership of
the United Network of Organ Sharing (UNOS) supporting the paired exchange
initiative, Garet Hil, Founder of the National Kidney Registry, announced
the results of recent match runs using donor chain matching. Combining
donors and recipients from 6 transplant centers, BestMatch, the Registry's
donor chain matching software, identified two perfect six antigen matches
between strangers. Studies show that perfectly matched living donor kidneys
add 10 years to the expected half-life of the transplanted kidney.
Analyzing the current Registry pool of 76 recipients, paired with 120
incompatible donors, 39 transplant opportunities were identified. All of
the transplants were well matched on both HLA and age criteria. The
majority of the matches identified by the system were more compatible than
is typical between a parent and child.
"We are not surprised by the results of the recent match runs given the
enormous mathematical advantages of donor chain matching over traditional
paired exchange matching. The advantages of donor chain matching improve
with larger pools because the number of possible transplants evaluated
increases geometrically with linear increases in pool size. We are
committed to working with UNOS to deliver these enhanced compatibility
benefits to all people facing kidney failure," said Garet Hil, Founder of
the Registry.
"Best Match has the potential to revolutionize living donor transplants.
The results of the latest match runs, including identification of perfect
six antigen matches between strangers, have exceeded our expectations in
this early developmental stage," said Rich Marta, the senior engineer
leading the BestMatch development project.
About the National Kidney Registry
The National Kidney Registry is a nonprofit 501(c)3 organization with a
mission to save and improve the lives of people facing kidney failure by
increasing the quality, speed, and number of living donor transplants in
the world.
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